欧洲肿瘤内科学会临床实践指南：乳腺癌易感基因突变携带者和其他乳腺卵巢遗传性癌症综合征的预防与筛查

　　2016年9月，欧洲肿瘤内科学会（ESMO）官方期刊、牛津大学出版社旗下《肿瘤学年鉴》正式发表以色列舍巴医学中心、葡萄牙尚帕利莫临床中心、瑞士圣乔瓦尼医院、西班牙瓦尔德西布伦大学医院、英国剑桥大学、波兰格但斯克医科大学起草的欧洲肿瘤内科学会（ESMO）临床实践指南：乳腺癌易感基因（BRCA）突变携带者和其他乳腺卵巢遗传性癌症综合征的预防与筛查。

Ann Oncol. 2016 Sep;27(suppl 5):v103-v110.

Prevention and screening in BRCA mutation carriers and other breast/ovarian hereditary cancer syndromes: ESMO Clinical Practice Guidelines for cancer prevention and screening.

Paluch-Shimon S, Cardoso F, Sessa C, Balmana J, Cardoso MJ, Gilbert F, Senkus E; ESMO Guidelines Committee.

Sheba Medical Center, Ramat Gan, Israel; Champalimaud Clinical Center, Lisbon, Portugal; Ospedale San Giovanni, Bellinzona, Switzerland; Vall d'Hebron University Hospital Institut d'Oncologia, Barcelona, Spain; University of Cambridge, Cambridge, UK; Medical University of Gdańsk, Gdańsk, Poland.

The guidelines will focus on cancer prevention and screening among individuals known to harbour a pathogenic BRCA1/2 mutation. The presence of a BRCA1 or BRCA2 mutation accounts for the majority of hereditary breast and ovarian cancer syndromes.

PMID: 27664246

DOI: 10.1093/annonc/mdw327