经皮神经电刺激与脉冲电磁场治疗坐骨神经疱疹后神经痛的比较研究

贵州医科大学     麻醉与心脏电生理课题组

翻译：刘云琴  编辑：陈锐  审核：曹莹

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目的:比较脉冲电磁场治疗（PEMFT）与经皮神经电刺激（TENS）治疗坐骨神经疱疹后神经痛的疗效。

方法:一项双盲随机临床研究包括56名患者（18名男性和38名女性）。参与者被随机均分为两组。两组均接受常规物理治疗。此外，A组接受TENS治疗，B组接受PEMFT治疗。两种方法均每日治疗一次，每周3次，每次20分钟，连续8周。干预前后对视觉模拟量表（VAS）和卡马西平摄入量（CMI）进行了评估。

结果:与治疗前相比，A组和B组治疗后VAS和CMI显著降低（P<0.001）。A组VAS和CMI的下降百分比分别为72.44%和69.47%，B组分别为68.95%和67.94%。研究结果显示，各组间VAS和CMI无显著差异（P>0.05）。A组和B组VAS和CMI均值分别为（2.4±0.78，204.5±16.76和2.67±0.9、210.57±16.5）。治疗后，两组间VAS和CMI的平均差异分别为(−0.27和−6.07）。

结论：通过VAS和CMI测量，TENS和PEMF在改善坐骨神经疱疹后神经痛方面均有效且几乎相等。应强调建议鼓励临床使用TENS和PEMF治疗坐骨神经疱疹后神经痛。

原始文献来源：Eid MM, Hamed NS, Abdelbasset WK, et. A comparative study between transcutaneous electrical nerve stimulation and pulsed electromagnetic field therapy in the management of post-herpetic neuralgia of the sciatic nerve. Medicine (Baltimore). 2022;101(44):e31433. 

英文原文

A comparative study between transcutaneous electrical nerve stimulation and pulsed electromagnetic field therapy in the management of post-herpetic neuralgia of the sciatic nerve

Abstract

Objectives: To compare the efficacy of pulsed electromagnetic field therapy (PEMFT) versus transcutaneous electrical nerve stimulation (TENS) in the treatment of post-herpetic neuralgia of the sciatic nerve. 

Methods: A double-blinded randomized clinical study has included 56 patients (18 males and 38 females). Participants were randomly and equally assigned into 2 groups. Both groups received conventional physical therapy treatment. Moreover, group (A) has an additional TENS, and group (B) had PEMFT. Both modalities were applied once daily, 3 times a week for 20 minutes for 8 successive weeks. Visual analog scale (VAS) and carbamazepine intake (CMI) dose have been assessed before and after interventions. 

Results: There was a significant decrease in VAS and CMI post-treatment in group A and B compared with that pretreatment (P < 0.001). The percent decrease in VAS and CMI in group A were 72.44% and 69.47% respectively and that for group B was 68.95% and 67.94% respectively. The findings revealed a non-significant difference in VAS and CMI (P > 0.05) between groups. The Means of VAS and CMI were (2.4 ± 0.78, 204.5 ± 16.76 and 2.67 ± 0.9, 210.57 ± 16.5) in group A and group B respectively. The mean difference for VAS and CMI was (-0.27 and -6.07) between groups post-treatment respectively. 

Conclusion: Both TENS and PEMFT were effective and nearly equivalent in improving the post-herpetic neuralgia of the sciatic nerve as measured by in VAS and CMI. Clinical recommendations should be highlighted to instigate the using of TENS and PEMFT in the management of post-herpetic neuralgia of the sciatic nerve