【罂粟摘要】STOP-Bang问卷作为阻塞性睡眠呼吸暂停术前筛查工具的验证：一项系统性评价和meta分析

STOP-Bang问卷作为阻塞性睡眠呼吸暂停术前筛查工具的验证：一项系统性评价和meta分析

贵州医科大学       麻醉与心脏电生理课题组

翻译：宋雨婷       编辑：宋雨婷       审校：曹莹

背景：

阻塞性睡眠呼吸暂停（OSA）是一种与术后并发症高度相关的常见疾病。STOP-Bang问卷是OSA的简单筛查工具。本系统性评价和meta分析旨在评估STOP-Bang问卷在手术人群队列中筛查 OSA 的有效性。

方法：

从2008年到2021年5月，对以下数据库进行了系统检索：MEDLINE、Medline-in-process、Embase、Cochrane 临床对照试验中心注册数据库、Cochrane系统性评价数据库、PsycINFO、Journals @ Ovid、Web of Science、Scopus和CINAHL。持续进行文献检索至2021年10月。

结果：

本次检索纳入了4641篇文章，其中10项研究共3247名受试者被纳入最终分析。受试者平均年龄为57.3±15.2岁，平均BMI为32.5±10.1kg/m²  。男性占47.4%。OSA的总患病率、中至重度OSA的患病率和重度OSA的患病率分别为65.2%、37.7%和17.0%。STOP-Bang问卷对所有OSA、中度至重度OSA和重度OSA的综合敏感性分别为85%、88%和90%，综合特异性分别为47%、29%和27%。所有OSA、中度至重度OSA和重度OSA的曲线下面积分别为0.84、0.67和0.63。

结论：

在术前评估中，STOP-Bang问卷可作为检测手术患者OSA的有效筛查工具，具有高敏感性和高鉴别力，可有效排除重度OSA，阴性预测值（指阴性受试者中真正未患病的比例）为93.2%。

原始文献来源：

Hwang M, Nagappa M, Guluzade N, Saripella A, Englesakis M, Chung F. Validation of the STOP-Bang questionnaire as a preoperative screening tool for obstructive sleep apnea: a systematic review and meta-analysis. BMC Anesthesiol. 2022;22(1):366.

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英文原文

Validation of the STOP-Bang questionnaire as a preoperative screening tool for obstructive sleep apnea: a systematic review and meta-analysis

Background: Obstructive sleep apnea (OSA) is a common disorder that is highly associated with postoperative complications. The STOP-Bang questionnaire is a simple screening tool for OSA. The objective of this systematic review and meta-analysis is to evaluate the validity of the STOP-Bang questionnaire for screening OSA in the surgical population cohort.

Methods: A systematic search of the following databases was performed from 2008 to May 2021: MEDLINE, Medline-in-process, Embase, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, PsycINFO, Journals @ Ovid, Web of Science, Scopus, and CINAHL. Continued literature surveillance was performed through October 2021.

Results: The systematic search identified 4641 articles, from which 10 studies with 3247 surgical participants were included in the final analysis. The mean age was 57.3 ± 15.2 years, and the mean BMI was 32.5 ± 10.1 kg/m2 with 47.4% male. The prevalence of all, moderate-to-severe, and severe OSA were 65.2, 37.7, and 17.0%, respectively. The pooled sensitivity of the STOP-Bang questionnaire for all, moderate-to-severe, and severe OSA was 85, 88, and 90%, and the pooled specificities were 47, 29, and 27%, respectively. The area under the curve for all, moderate-to-severe, and severe OSA was 0.84, 0.67, and 0.63.

Conclusions: In the preoperative setting, the STOP-Bang questionnaire is a valid screening tool to detect OSA in patients undergoing surgery, with a high sensitivity and a high discriminative power to reasonably exclude severe OSA with a negative predictive value of 93.2%.