常见的小圆细胞肿瘤有哪些

小圆细胞肿瘤是病理学概念，对于组织来源不易判断的描述，镜下肿瘤细胞呈圆形，形态偏小，类似于成熟的淋巴细胞，不同于大圆细胞和梭形细胞，小圆细胞肿瘤见于多种肿瘤，包括未分化的恶性肿瘤，预后较差，常见于青少年。

（Chronic Lymphocytic Leukemia (CLL) ）

Round cell tumors as the name suggest are comprised round cells with increased nuclear-cytoplasmic ratio. This group of tumor includes entities such as peripheral neuroectodermal tumor, rhabdomyosarcoma, synovial sarcoma, non-Hodgkin's lymphoma, neuroblastoma, hepatoblastoma, Wilms' tumor, and desmoplastic small round cell tumor. These round cells tumors are characterized by typical histological pattern, immunohistochemical, and electron microscopic features that can help in differential diagnosis.

（doi: 10.4103/ijmpo.ijmpo_84_16）Round cell tumors as the name suggest are comprised round cells with increased nuclear-cytoplasmic ratio. This group of tumor includes entities such as peripheral neuroectodermal tumor, rhabdomyosarcoma, synovial sarcoma, non-Hodgkin's lymphoma, neuroblastoma, hepatoblastoma, Wilms' tumor, and desmoplastic small round cell tumor. These round cells tumors are characterized by typical histological pattern, immunohistochemical, and electron microscopic features that can help in differential diagnosis. The present article describes the classification and explains the histopathology and immunohistochemistry of some important round cell tumors.

肉瘤，Ewing肉瘤为原始的小圆细胞肿瘤，存在FET，EWSR1，CD99、NKX2.2阳性，瘤细胞比淋巴细胞稍大（1-2倍），胞质稀少。低分化滑膜肉瘤。

原始神经外胚层肿瘤，Primitive neuroectodermal tumor (PNET)。