翻看下日历，这都1月24号啦，留给中国队的时间不多了！
幸好川普又让Pubmed活过来了（讲真，Pubmed也没死啊~）；幸好，StarBase又可以用了；幸好核酸研究又放出了一大波的数据库。。。（doi: 10.1093/nar/gkx1235）。
快扒拉扒拉看看能不能从这些数据库里补足自己立项的论据！
2018年Nucleic Acids Research数据库特辑上发表的新数据库
DatabaseURLBrief description
3DIVhttp://kobic.kr/3div3D-genome Interaction Viewer and database
AAgMarkerhttp://bioinfo.wilmer.jhu.edu/AAgMarker/index.jspSerum autoantigen biomarkers from proteome microarrays
aBiofilmhttp://bioinfo.imtech.res.in/manojk/abiofilm/Anti-biofilm compounds
ActiveDriverDBhttps://activedriverdb.org/Genome variation mapped against post-translational modifications
ADReCS-Targethttp://bioinf.xmu.edu.cn/ADReCS-TargetAdverse Drug Reactions linked to proteins, genes and genetic variants
AmyProhttp://amypro.netProteins with validated amyloidogenic regions
anti-CRISPRdbhttp://cefg.uestc.edu.cn/anti-CRISPRdb/anti-CRISPR proteins
AraGWAS Cataloghttps://aragwas.1001genomes.orgArabidopsis Genome-Wide Association Studies
ASpediahttp://combio.snu.ac.kr/aspediaAlternative Splicing Encylopedia
ChannelsDBhttp://ncbr.muni.cz/ChannelsDBChannels, pores and tunnels found in biomacromolecular structures
CirGRDBhttp://cirgrdb.biols.ac.cnRegulation of RNAs in circadian rhythms
ClusterCADhttps://clustercad.jbei.org and http://clustercad.igb.uci.eduEngineering of type I modular polyketide synthases
CR2Cancerhttp://cis.hku.hk/CR2CancerChromatin Regulators and Cancer
CSCDhttp://gb.whu.edu.cn/CSCDCancer-Specific cRNA Database
dbCAN-seqhttp://cys.bios.niu.edu/dbCANGenome scale CAZymes and CAZyme gene clusters
dbCoRChttp://dbcorc.cam-su.org/Core transcriptional Regulatory Circuit models
DifferentialNEThttp://netbio.bgu.ac.il/diffnetDifferential protein-protein interactions in human tissues
DiseaseEnhancerhttp://biocc.hrbmu.edu.cn/DiseaseEnhancer/Enhancer-disease associations
DISNORhttp://disnor.uniroma2.it/Protein interaction networks linking disease genes
DreamBASEhttp://rna.sysu.edu.cn/dreamBaseHuman expressed pseudogenes: DNA Modification, RNA Regulation and bound proteins
ECOdrughttp://www.ecodrug.orgEvolutionary COnservation of Drug targets
EpiDenovohttp://61.148.58.210:8080/EpiDenovo/The epigenome in mammalian embryonic development
EPDhttps://peptracker.com/epd/Encyclopedia of Protein Dynamics
EVLncRNAshttp://biophy.dzu.edu.cn/EVLncRNAs/Experimentally Validated lncRNAs including disease indications
eRAMhttp://www.unimd.org/eram/Annotated rare diseases
ExoRBasehttp://www.exoRBase.orgHuman blood exosome RNAs
FlavorDBhttp://cosylab.iiitd.edu.in/flavordbFlavour molecules
FusionDBhttp://services.bromberglab.org/fusiondb/Functional-repertoire similarity-based organism network
GVMhttp://bigd.big.ac.cn/gvm/Genome Variation Map
HCMDBhttp://hcmdb.i-sanger.com/indexHuman Cancer Metastasis DataBase
HEDDhttp://zdzlab.einstein.yu.edu/1/hedd.phpHuman Enhancer Disease Database
ICGhttp://icg.big.ac.cnInternal Control Genes for RT-qPCR normalization
IMOTAhttps://ccb-web.cs.uni-saarland.de/imota/Interactive Multi-Omics-Tissue Atlas
iPTMnethttp://research.bioinformatics.udel.edu/iptmnet/Post-Translational Modification networks
ITSoneDBhttp://itsonedb.cloud.ba.infn.it/Eukaryotic ribosomal RNA Internal Transcribed Spacer 1 sequences
jMorphttps://jmorp.megabank.tohoku.ac.jp/Metabolomics and proteomics of 1000 healthy Japanese people
LINCS Data Portalhttp://lincsportal.ccs.miami.edu/dcic-portal/Cell-based perturbation-response signatures
LinkedOmicshttp://www.linkedomics.orgMulti-omics analysis of 32 cancers
Lnc2Methhttp://www.bio-bigdata.com/Lnc2MethlncRNAs and DNA methylation
m6AVarhttp://m6avar.renlab.org/Human variants affecting m6A sites
MeDReadershttp://medreader.org/Transcription factors binding methylated DNA
microbiomeDBhttp://microbiomeDB.orgMining and analysing microbiome data
MINTbasehttps://cm.jefferson.edu/MINTbase/Mitochondrial and nuclear tRNA fragments
miRCartahttps://mircarta.cs.uni-saarland.de/miRNAs and precursors
mirTranshttp://mcube.nju.edu.cn/jwang/lab/soft/mirtrans/Cell-specific transcriptional information for human miRNAs
MISThttp://fgrtools.hms.harvard.edu/ProteinSearch/Model organism molecular interaction data
MGAhttp://ccg.vital-it.ch/mga/Mass Genome Annotation
MMPhttps://mmp.sfb.uit.no/databases/Marine Metagenomics Portal
MSDDhttp://www.bio-bigdata.com/msdd/miRNA SNP Disease Database
mSignatureDBhttp://tardis.cgu.edu.tw/msignaturedbMutational signatures in human cancers
MVPhttp://mvp.medgenius.infoMicrobe-phage interactions
NPASShttp://bidd2.nus.edu.sg/NPASS/Natural Product quantitative Activities
OverGeneDBhttp://overgenedb.amu.edu.plOverlapping protein-coding genes
PAMDBhttp://pseudomonas.umaryland.eduPseudomonas aeruginosa Metabolome DataBase
PancanQTLhttp://bioinfo.life.hust.edu.cn/PancanQTL/Expression quantitative loci (eQTL) analysis of cancer samples
PedAMhttp://www.unimd.org/pedam/Pediatric Disease Annotation & Medicine
PCSDhttp://systemsbiology.cau.edu.cn/chromstatesPlant Chromatin State Database
PGG.Populationhttps://www.pggpopulation.orgGenomic diversity of diverse human populations
PharmacoDBhttp://pharmacodb.pmgenomics.caPharmacogenomics of cancer cell lines
PICKLEShttp://pickles.hart-lab.orgPooled In-vitro Crispr Knockout Library Essentiality Screens
PIT-DBhttp://pitdb.orgProteomics Informed by Transcriptomics
Planteomehttp://www.planteome.orgPortal for plant ontologies and annotations
PopHumanhttp://pophuman.uab.catPopulation genomics-oriented genome browser
qPrimerDBhttp://biodb.swu.edu.cn/qprimerdbqPCR primers for 200 organisms
RISEhttp://rise.zhanglab.netRNA-RNA interactions
RNArchitecturehttp://iimcb.genesilico.pl/RNArchitecture/Structural classification of RNAs
SBCCDBhttp://sbcddb.moffitt.orgSleeping Beauty Cancer Driver DataBase
SCPortalenhttp://single-cell.clst.riken.jp/Human and mouse single-cell centric database
SEECancerhttp://biocc.hrbmu.edu.cn/SEECancerEvolutionary-stage specific somatic events in cancer
StemMapperhttp://stemmapper.sysbiolab.euStem cell gene expression
STCRDabhttp://opig.stats.ox.ac.uk/webapps/stcrdabStructural T-Cell Receptor Database
SysteMHC Atlashttps://systemhcatlas.org/Immunopeptidomics of MHC-bound peptides
Tabloid Proteomehttp://iomics.ugent.be/tabloidproteomeProtein associations inferred from Mass Spectrometry
Target-Pathogenhttp://target.sbg.qb.fcen.uba.ar/pathoDrug target optimisation in pathogens
TC3Ahttp://tc3a.org/3’ untranslated regions, alternative polyadenylation and cancer
TissGDBhttp://zhaobioinfo.org/TissGDBTissue-specific Gene DataBase in cancer
TranslatomeDBhttp://www.translatomedb.net/Translatome data from RNC-Seq and Ribo-Seq
TriForC databasehttp://bioinformatics.psb.ugent.be/triforc/Triterpene pathways
TCSBNhttp://inetmodels.comTissue and Cancer-Specific Biological Networks
VarCardshttp://varcards.biols.ac.cn/Interpretation of coding variants in the human genome
VDJdbhttps://vdjdb.cdr3.net/.T-cell receptor sequences with known antigen specificity
Virus Taxonomyhttp://ictv.globalTaxonomy of viruses
2018年Nucleic Acids Research更新了的老数据库
DatabaseURLBrief description
BioMuta and BioExpresshttps://hive.biochemistry.gwu.edu/biomuta and https://hive.biochemistry.gwu.edu/bioxpressCancer SNVs and gene expression
BioStudieshttps://www.ebi.ac.uk/biostudies/Data of all kinds relating to a single study
iSyTEhttp://research.bioinformatics.udel.edu/iSyTEintegrated Systems Tool for Eye gene discovery
miRandolahttp://mirandola.iit.cnr.it/Extracellular and circulating non-coding RNAs
mirDIPhttp://ophid.utoronto.ca/mirDIP/microRNA Data Integration Portal
MNDRhttp://www.rna-society.org/mndr/Mammal ncRNA-Disease Repository
NLSdbhttps://rostlab.org/services/nlsdb/Nuclear Localization Signals
PAGER 2.0http://discovery.informatics.uab.edu/PAGER/Pathway, Annotated-list, and Gene-signature Electronic Repositor
ProteomicsDBhttps://www.ProteomicsDB.orgMass spectrometry of the human proteome
PULDBhttp://www.cazy.org/PULDB new/Polysaccharide Utilization Loci in Bacteroidetes species
ReMaphttp://remap.cisreg.euTranscription factor ChIP-seq data
RMDBhttp://rmdb.stanford.eduStructure mapping of RNA
SuperDrug2http://cheminfo.charite.de/superdrug2Approved drugs
TRRUST v2http://www.grnpedia.org/trrust/Transcriptional regulatory interactions in human and mouse
TumorFusionshttp://www.tumorfusions.orgTumour fusion genes
小结：NAR里也不乏很多灌水的数据库，纯粹是为了发文章，弄不好今年发了文章，明年服务器就停了，网站也登不上了，那些坚持更新的是真的良心呐~今年又更新了这么一大波数据库，大家看看有没有自己领域相关的吧，至少这会这些数据库还都是能用的。有些国外网站可能不太好登，大家各凭本家啦！
