自身免疫性肝炎（AIH）是遗传易感个体在环境等因素诱导下出现的自身免疫性肝病，以血清自身抗体阳性、高免疫球蛋白G血症、转氨酶水平升高和界面性肝炎为主要特征。AIH发病机制尚未完全阐明，临床诊治过程中亦有较高异质性，患者个体化的精准医学诊疗显得尤为重要。为此，结合近年来本领域重要研究进展和难点问题进行述评。
Autoimmune hepatitis (AIH) is an autoimmune liver disease induced by environmental factors in individuals with genetic susceptibility, with the main features of positive serum autoantibody, hypergammaglobulinemia, elevated transaminases, and interface hepatitis. The pathogenesis of AIH remains unknown, high heterogeneity is observed in clinical diagnosis and treatment, and thus it is of great importance to establish individualized precise diagnosis and treatment. Therefore, this article reviews the research advances and difficult issues in this field.
【引证本文】：WANG QX, MA X. Current status and perspectives of autoimmune hepatitis［J］. J Clin Hepatol, 2020, 36(4): 721-723. (in Chinese)
王绮夏， 马雄. 自身免疫性肝炎的研究现状与展望［J］. 临床肝胆病杂志, 2020, 36(4): 721-723.
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