[1]Tomas C, Newton J. Metabolic abnormalities in chronic fatigue syndrome/myalgic encephalomyelitis: a mini-review. Biochem Soc Trans. 2018;46(3):547-553.[2]Guo C, Che X, Briese T, et al. Deficient butyrate-producing capacity in the gut microbiome is associated with bacterial network disturbances and fatigue symptoms in ME/CFS. Cell Host Microbe. 2023;31(2):288-304.e8.[3]J. Schulthess, S. Pandey, M. Capitani, et al., The short chain fatty acid butyrate imprints an antimicrobial program in macrophages. Immunity, 50 (2019), pp. 432-445.e7, 10.1016/j.immuni.2018.12.018[4]J.G. LeBlanc, F. Chain, R. Martín, et al., Beneficial effects on host energy metabolism of short-chain fatty acids and vitamins produced by commensal and probiotic bacteria. Microb. Cell Fact., 16 (2017), p. 79.[5]Campagnolo, N., Johnston, S., Collatz, A., et al., Dietary and Nutrition Interventions for the Therapeutic Treatment of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis: A Systematic Review. J. Hum. Nutr. Diet. 2017, 30, 247–259.[6]Sullivan, Å., Nord, C.E. & Evengård, B. Effect of supplement with lactic-acid producing bacteria on fatigue and physical activity in patients with chronic fatigue syndrome. Nutr J 8, 4 (2009).[7]Borody, T.J., Nowak, A., Finlayson, S. The GI Microbiome and Its Role in Chronic Fatigue Syndrome: A Summary of BacteriotherapyThe GI Microbiome and Its Role in Chronic Fatigue Syndrome: A Summary of Bacteriotherapy. ACNEM J. 2012, 31, 3–8.[8]Borody, T. Bacteriotherapy for Chronic Fatigue Syndrome: A Long-Term Follow up Study. In Proceedings of the 1995 CFS National Consensus Conference; 1995. 本文为科普中国·星空计划扶持作品作者|赵蓓 科普创作者审核|王强 北京协和医院消化内科 副主任医师出品|中国科协科普部监制|中国科学技术出版社有限公司、北京中科星河文化传媒有限公司