任何情况下,对药物过敏必须停用该药。他汀也不例外。
■ 1.如果是单纯血脂升高,血脂恢复正常后,可以试着停药,但必须复查血脂,3个月后复查血脂,通过健康饮食、坚持运动等健康生活前提下,如果停药后LDL-C能够维持在3.4 mmol/L以下,则无需继续服用他汀。
■ 1.血脂正常,停药后,血脂再次升高:如果停用他汀后,胆固醇过了几个月又再次升高,说明不能停药。停药后,一部分的LDL-C会再次升高,这部分患者需要长期服用他汀,尤其是遗传性导致的家族性高胆固醇血症(FH)患者,因为自身代谢出现了问题。
对于明确心脑血管疾病,如冠心病、心绞痛、心肌梗死、心脏支架植入术后、心脏搭桥术后、严重颈动脉狭窄、脑梗死等的ASCVD患者,他汀有两个作用:1)降低LDL-C,从而预防和控制心脑血管疾病;2)抗炎稳定斑块,预防血管斑块加重、血管缺血、斑块破裂、血栓、心肌梗死、脑梗死等。
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