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实现人狗共同长寿?

Can old dogs teach us new tricks? 

老狗身上能研究出新东西吗?

Scientists are looking for 10,000 pets for the largest-ever study of aging in canines. 

科学家们正在征集一万只宠物用于史上最大型的犬类老化研究。

They hope to shed light on human longevity too.他们也希望能解开人类长寿之谜。

.

The project will collect a pile of pooch data: vet records, DNA samples, gut microbes and information on food and walks. 

该项目会收集各种犬类数据:就诊记录,DNA样本,内脏微生物以及关于食物和遛狗的信息。

Five hundred dogs will test a pill that could slow the aging process.

有五百只狗会参与一种能够延缓衰老的药片的测试。

“What we learn will potentially be good for dogs and has great potential to translate to human health,” said project co-director Daniel Promislow of the University of Washington School of Medicine.

“我们的成果可能会对狗狗有益,并可能会间接转化为对人类健康有用的结果,”该项目的联合主席来自华盛顿大学医学院的丹尼尔·普罗米思罗说道。

If scientists find a genetic marker for a type of cancer in dogs, for instance, that could be explored in humans.

比方说,如果科学家在狗种找到了一个跟癌症相关的基因,这种基因很可能在人类中 也会存在。

For the study, the dogs will live at home and follow their usual routine. 

在这项研究中,狗狗们会待在家里维持自己的日常。

All ages and sizes, purebreds and mutts are welcome.

各种年龄,大小,纯种和杂种狗都可以加入该项目。

Owners will complete periodic online surveys and take their dogs to the vet once a year, with the possibility of extra visits for certain tests. 

狗主人需要定期完成网上调查问卷,然后每年带他们的狗狗去一次兽医处,中间可能还会有额外的某些测试。

Their welfare will be monitored by a bioethicist and a panel of animal welfare advisers.

它们的福利会受到动物论理学家和一些动物福利顾问的监管。

To nominate a pet, owners can visit the Dog Aging Project’s website.

如果想给自家宠物报名,主人们可以访问狗狗老化项目网站。

The five-year study was formally launched Thursday at a science meeting in Austin, Texas. 

这个为期五年的项目于周四在德州奥斯汀市的一个科学会议上正式启动。

The National Institute on Aging is paying for the $23 million project because dogs and humans share the same environment, get the same diseases and dogs’ shorter lifespans allow quicker research results, said deputy director, Dr. Marie Bernard. 

国家老化研究所给这个项目投资了两千三百万美元,因为狗狗与人类有共同的生活环境,很多疾病也相同,而狗狗更短的生命周期可以让我们更快得到研究结果,副主任玛丽·伯纳德博士说道。

The data collected will be available to all scientists.

所收集到的数据将提供给所有的科学家。

Leslie Lambert of Parkville, Maryland, enrolled her 11-year-old rescue dog, Oscar, in an early phase.

来自马里兰市帕克维尔郡的莱斯利·兰伯特在项目早期就给她十一岁的搜救犬奥斯卡报了名。

“I would selfishly like to have him around forever,” said the 33-year-old veterinarian.

“我私心想让它永远陪着我,”这位33岁的兽医说道。

 “Unfortunately, he ages much, much faster than I do.”

“可惜的是,它比我老得快得多得多。”

But she’s torn by the prospect of an anti-aging pill because so many abandoned dogs go without care. 

但考虑到抗衰老药物的前景她感到忧心,因为还有很多流浪狗得不得关怀。

“Just because we can, should we?”

“仅仅因为我们能做到,我们就该去做吗?”

Compared to farm dogs in the past, today’s pampered pups live longer and get more geriatric diseases, said veterinarian Dr. Kate Creevy of Texas A&M University, the project’s chief scientific officer.

跟过去农场上的狗相比,如今的得到精心照料的狗狗们活得更长了,也会得更多的老年病,兽医凯特·克里夫博士说道,他来自德州大学也是该项目的首席科学主管。

Yet no standard measures exist for frailty or prognosis in sick, aged dogs, Creevy said. 

不过目前还没有针对老年和患病狗狗的脆弱和预后的相关标准,克里夫说道。

The project will develop those tools.

该项目也会研发与此相关的内容。

One dog year is roughly equal to seven human years, Creevy said, but that varies by breed. Large dogs have shorter lifespans than smaller dogs.

狗狗活一年大概相当于人类活七年,克里夫说道,但这又随着狗狗品种不同而有所差异。大型狗狗比小型狗生命周期更短。

 A Great Dane’s lifespan is about half that of a toy poodle’s.

一只大型丹麦犬的寿命大概只有小型玩具贵宾犬的一半。

That makes large dogs better test subjects for the pill. 

因此大型狗狗更适合测试这种药片。

Dogs weighing at least 40 pounds will be eligible for an experiment with rapamycin, now taken by humans to prevent rejection of transplanted kidneys. 

体重40磅以上的狗狗有资格参与雷帕霉素的测试,这是一种用来对抗肾移植后排异反应的药物。

The drug has extended lifespan in mice.

这种药物已经证实可以延长鼠类的寿命。

 A small safety study in dogs found no dangerous side effects, said project co-director Matt Kaeberlein of the University of Washington.

在狗狗中进行的小型安全性测试发现它没有什么危险的副作用,该项目的联合主席华盛顿大学的马特·凯博林说道。

Human devotion to dogs drives projects like this, the scientists said. 

人类对狗狗的挚爱催生了这类项目,科学家们说道。

Owners will gladly fill out surveys, send records and submit a pup’s poop for analysis if they think it will help all dogs live longer, even if it won’t help their pet.

如果狗主人们知道这可以帮狗狗活得更久,他们就很乐意填问卷调查,发送记录,并将狗狗的粪便样品送去作分析,哪怕帮不上自己的狗狗。

“People love dogs,” said Promislow, who normally studies aging in fruit flies. “No one has ever come up to me and said, 'Oh my goodness, I just love fruit flies.’”

“人们真的爱狗,”普洛斯米罗说道,他一般研究的是果蝇的衰老。"没人跑来跟我说,'噢天哪,我太爱果蝇了。’

问题

根据文中提到内容,以下哪种狗寿命最长?

A.大丹麦犬

B.德国黑背

C.贵宾犬

D.金毛犬

留言回复正确答案,前十名朋友可以获得红包奖励哦,赶快来试试吧!

| END |

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