Changes in Cortical Dopamine D1 Receptor Binding Associated with Cognitive Training
认知训练或能改变皮质多巴胺D1受体的浓度
Science 6 February 2009:
Vol. 323 no. 5915 pp. 800-802
DOI: 10.1126/science.1166102
Working memory is a key function for human cognition, dependent on adequate dopamine neurotransmission. Here we show that the training of working memory, which improves working memory capacity, is associated with changes in the density of cortical dopamine D1 receptors. Fourteen hours of training over 5 weeks was associated with changes in both prefrontal and parietal D1 binding potential. This plasticity of the dopamine D1 receptor system demonstrates a reciprocal interplay between mental activity and brain biochemistry in vivo.
工作记忆是人类认知的关键功能，它需要大量多巴胺的神经传递。本研究中我们会看到，对工作记忆的训练，也就是提高工作记忆的容量，与皮质多巴胺的D1受体的浓度相关。5周之内进行14个小时的训练与额叶和顶叶的D1受体浓度变化有潜在的联系。多巴胺D1受体的可塑性表明人类的心智活动与大脑的生物化学过程之间的互益关系（reciprocal interplay）
http://www.sciencemag.org/content/323/5915/800.short
本站仅提供存储服务，所有内容均由用户发布，如发现有害或侵权内容，请
点击举报。
