地塞米松对未足月胎膜早破孕妇妊娠结局的影响

【摘要】 目的 探究地塞米松?ξ醋阍绿ツぴ缙圃懈救焉锝峋值挠跋臁７椒? 70例未足月胎膜早破孕妇， 随机分为对照组和观察组， 每组35例。对照组孕妇未使用地塞米松， 观察组孕妇实施地塞米松治疗。比较两组孕妇妊娠结局、新生儿预后情况、破膜至分娩时间及产程。结果 观察组孕妇脐带脱垂、产后出血、剖宫产、死产及新生儿死亡发生率均低于对照组， 差异具有统计学意义（P<0.05）。治疗后， 观察组新生儿apgar评分为（8.06±3.44）分，="" 对照组新生儿apgar评分为（5.16±3.57）分，="" 观察组新生儿apgar评分高于对照组，="" 差异具有统计学意义（t="3.461，"><0.05）。观察组孕妇破膜至分娩时间及产程均短于对照组，><0.05）。结论 地塞米松治疗未足月胎膜早破孕妇能有效缩短破膜至分娩时间及产程，="" 提高产妇生产的安全性及新生儿的存活率，="" 并能有效减少新生儿不良情况的发生，="">临床应用中具有较高的推广价值。

【关键词】 地塞米松；未足月胎膜早破；妊娠结局
DOI：10.14163/j.cnki.11-5547/r.2017.17.059
Influence by dexamethasone on pregnancy outcome in pregnant women with preterm premature rupture of membranes LIN Jue-ying. Department of Obstetrics， Jieyang City People’s Hospital， Jieyang 522000， China
【Abstract】 Objective To investigate influence by dexamethasone on pregnancy outcome in pregnant women with preterm premature rupture of membranes. Methods A total of 70 pregnant women with preterm premature rupture of membranes were randomly divided into control group and observation group， with 35 cases in each group. The control group did not receive dexamethasone， and the observation group received dexamethasone for treatment. Comparison was made on pregnancy outcome， neonatal prognosis， duration from rupture of membranes to delivery， and stages of labor between the two groups. Results The observation group had all lower incidence of prolapse of cord， postpartum hemorrhage， cesarean sec， stillbirth and perinatal mortality than the control group， and their difference had statistical significance （P<0.05）. after="" treatment，="" the="" observation="" group="" had="" neonatal="" apgar="" score="" as="" （8.06±3.44）="" points，="" and="" the="" control="" group="" had="" neonatal="" apgar="" score="" as="" （5.16±3.57）="" points.="" the="" observation="" group="" had="" higher="" neonatal="" apgar="" score="" than="" the="" control="" group，="" and="" their="" difference="" had="" statistical="" significance="" （t="3.461，"><0.05）. the="" observation="" group="" had="" all="" shorter="" duration="" from="" rupture="" of="" membranes="" to="" delivery，="" and="" stages="" of="" labor="" than="" the="" control="" group，="" and="" the="" difference="" had="" statistical="" significance=""><0.05）. conclusion="" in="" treating="" pregnant="" women="" with="" preterm="" premature="" rupture="" of="" membranes，="" dexamethasone="" can="" effectively="" shorten="" duration="" from="" rupture="" of="" membranes="" to="" delivery="" and="" stages="" of="" labor，="" improve="" safety="" for="" puerpera="" and="" survival="" rate="" of="" newborn，="" and="" decrease="" occurrence="" of="" neonatal="" adverse="" reactions.="" this="" method="" contains="" highly="" promoting="" value="" in="" clinical="" application.="">
【Key words】 Dexamethasone； Preterm premature rupture of membranes； Pregnancy outcome